Cushing syndrome also called “Hypercortisolism” is a rare disorder resulting from the excessive production of the hormone cortisol. The overproduction of cortisol can be due to a tumor in the pituitary gland or a benign or cancerous tumor in the adrenal gland. It may also be caused due to overuse of corticosteroid medications — when used for a long time period, this medication starts mimicking the effects of cortisol.

Cortisol also called the “stress hormone” helps the body respond to stress and change. The excessive production of this hormone can affect all organs and tissues of the body. These effects are collectively called “Cushing Syndrom.” If left untreated, it can cause high blood pressure, obesity, heart attacks, Type 2 Diabetes, and other serious conditions.

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    People with this syndrome may gain weight in unusual ways. Common symptoms include:

    • Round face (moon face)
    • Fat deposit between the shoulder and upper back causing a visible hump
    • Stretch marks on arms, thighs, breasts, and abdomen
    • Fragile and thin skin
    • High blood sugar
    • Muscle and Bone Weakness
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    If you experience any symptoms of Cushing Syndrome, your doctor may start the diagnosis by reviewing your medications – pills, inhalers, and injections. Symptoms like weight gain or fatigue are common so he or she might order some other tests for an accurate diagnosis. The tests may include:

    • A 24-hour urinary cortisol test
    • Saliva test
    • Blood tests
    • Imaging tests
    • Petrosal sinus sampling
    • (MRI) pituitary and MRI abdomen
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    There are various options for Cushing syndrome treatment. In severe cases, surgery may be required to remove the tumor or adrenal or pituitary gland. Other treatments include the use of certain medications, chemotherapy, and radiation.

    Why Choose Us?

    At Southern California Brain & Spine Surgery, we offer an integrated and holistic approach to your care. Our doctor, Dr. Moksha Ranasinghe — a board-certified neurosurgeon — has extensive experience working with patients affected by Huntington’s disease and other neurological disorders such as Cushing Syndrome and Hydrocephalus. She looks into the patient’s medical history and develops a patient-focused treatment plan.


    Advanced diagnostic methods


    State-of-the-art technology


    Minimal Invasive Surgery


    Recovery with less downtime


    Patient-centered approach


    Outstanding patient care

    For more information call us at 213-369-4583 or visit our office in Los Angeles today!

    Frequently Asked Questions

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    What is Exogenous Syndrome?

    Exogenous Syndrome is a type of Cushing syndrome that is caused due to intake of medications such as prednisone. When taken for a long time, this drug starts mimicking the effects of cortisol.

    What is Endogenous Syndrome?

    The endogenous syndrome is a rare condition that occurs when the adrenal gland starts producing too much cortisol in the body. The reason for Cushing syndrome is internal, that’s why it is called Endogenous Syndrome.

    What is Cushing Syndrome life expectancy?

    Cushing syndrome is a serious condition and can be fatal if left untreated. In severe cases, the average survival period is 4 to 5 years.